Next-Gen Therapies and Smart Diagnostics
Our innovations spanning cancer treatment, regenerative medicine, gene editing, point of care IVD, and novel medical devices.
CAR-T and TCR Therapies
- CAR-T Cell Therapies: Chimeric Antigen Receptor T-cell (CAR-T) therapies continue to dominate the field, representing 49% of genetically modified cell therapies in development. While initially focused on blood cancers, their application is expanding to solid tumors and autoimmune diseases .
- TCR Therapies: T-cell Receptor (TCR) therapies are gaining traction, offering precision targeting of cancer cells by recognizing specific antigens presented by tumor cells
Cost effective Cell and Gene therapy Therapy Manufacturing
- To address the high costs and complexity of cell therapies, our engineers developing innovations and solutions to make treatments more affordable and widely available by enabling large-scale manufacturing .
Exosome-based Regenerative Therapies
MSC-derived exosomes for wound healing, cardiac repair, neuro-regeneration, and arthritis.
They modulate inflammation, promote angiogenesis, and enhance tissue repair without the risks of cell-based therapy (e.g., immune rejection, tumorigenicity).
Clinical-Grade Manufacturing & Isolation
Innovations in GMP-compliant, scalable production: Use of bioreactors, tangential flow filtration, and chromatography to improve purity and yield.
Improved standardization protocols for characterization and quality control.
Oncology Applications
Tumor-derived exosomes used as personalized vaccines (carrying tumor antigens).
Engineered exosomes as immune checkpoint inhibitors, or to reprogram tumor-associated macrophages.
CRISPR-Based Therapies
We employ groundbreaking CRISPR-based therapy edits blood-forming stem cells to produce fetal hemoglobin, offering relief to patients with sickle cell disease and transfusion-dependent beta thalassemia.
Stem Cell Innovations
- Heart Failure in Children: Researchers are developing stem cell therapies to treat heart failure in children by reprogramming blood cells into heart cells. Lab-grown heart organoids and engineered heart tissue sheets are being prepared for clinical trials, aiming to repair damaged hearts .
- Blood Aging and Limb Regeneration: Studies have uncovered mechanisms behind blood stem cell aging and identified genes like Hand2 that guide limb regrowth in salamanders. These findings could inform future therapies for rejuvenation and tissue regeneration in humans .
Exosome-mimetic Nanoparticles
Artificially synthesized vesicles that mimic exosomes but offer higher scalability, purity, and engineering control.
Used to overcome production and heterogeneity challenges of natural exosomes.
Immune Modulation
Exosomes derived from dendritic cells, Tregs, or mesenchymal stem cells can suppress or modulate immune responses, useful in autoimmune diseases, transplant tolerance, and graft-versus-host disease.
Diagnostics + Therapeutics (Theranostics)
Dual-role exosomes used for targeted drug delivery and real-time imaging via incorporation of contrast agents or fluorescent tags. Potential to monitor therapeutic response and disease progression.
Discover Breakthrough Innovations
Delve into pioneering advancements in cancer therapies, gene editing, and regenerative medicine that redefine healthcare possibilities.
CAR-T and TCR Therapy Advances
Cellular Immunotherapy
CRISPR-Based Gene Editing
Precision Genetic Treatments
Regenerative Exosome Therapies
Next-Gen Healing Solutions
